Tag Archives: epigenetics

genetics of kidney stones

Genetics of Kidney Stones

Kidney stone development is the composite end-result of multiple factors including genetic, dietary and environmental, and can have serious consequences. They are often painful and if left unaddressed can lead to more severe conditions such as obstruction of urinary flow and permanent damage to the kidneys. Recurrent kidney stones are one of the common causes…

Picture of Arsenic in the periodic table

Arsenic and Kidney Health

You might be surprised to learn that arsenic is micromineral naturally found in our food and in the soil. However, in higher amounts arsenic is a toxic heavy metal. Even though arsenic poisoning is lethal, it’s important to realize that lower level chronic exposure to arsenic can negatively impact kidney health. By Majd Isreb, MD,…

Pharmacogenomics: Advances in Individualized Kidney Treatment

Pharmacogenomics: Advances in Individualized Treatment in Kidney Disease

By Lara Zakaria, RPh MS CNS CDN IFMCP According to a report by the US Food and Drug Administration (FDA), 2.2 million adverse drug reactions (ADRs) occur in the US annually. On the other hand, the healthcare cost and morbidity associated with ineffective medication causes unnecessary burden as well as of patient confidence in treatment. Clinicians…

IgA nephropathy is caused by a trigger that causes the gut to produce abnormal IgA that causes kidney damage

IgA nephropathy: A target for Integrative approach

Immunoglobulin A (IgA) nephropathy is a prime example of the interplay of genetics, epigenetics, leaky gut, environment and diet affects and influence the development of kidney disease. What is IgA? Immunoglobulins are a large protein structure that is part of the adaptive immune system. There are various types, categorized by a letter and sometimes a…