Evidence-Based Integrative Nephrology for Health Professionals
Expand your approach to kidney care through clinical education that connects conventional nephrology with nutrition, lifestyle medicine, genetics and epigenetics, environmental health, the gut–kidney connection, and appropriate pharmaceutical care.
A Broader Lens on Kidney Care
Integrative nephrology does not replace evidence-based kidney care. It expands the clinical lens.
Kidney health is influenced by interconnected biological, metabolic, environmental, nutritional, and lifestyle factors. At the Integrative Kidney Institute, we explore these connections while remaining grounded in kidney physiology, clinical evidence, and established standards of care.
Our Six-Pillar Framework
Genetics & Epigenetics
Explore how inherited risk, gene–environment interactions, and epigenetic regulation may influence kidney disease susceptibility and progression.
Nutrition
Examine dietary patterns, nutrients, metabolic health, and the evolving evidence surrounding nutrition in kidney disease.
Lifestyle
Understand the roles of physical activity, sleep, stress, circadian biology, and other lifestyle factors in kidney and cardiovascular health.
Environmental Health
Explore how pollutants, occupational exposures, and other environmental factors may affect kidney function and long-term kidney health.
Gut & Microbiome
Follow emerging research into the gut–kidney axis, microbial metabolites, intestinal barrier function, inflammation, and uremic physiology.
Pharmaceutical Care
Integrate evidence-based pharmacologic therapy with attention to medication effects, interactions, kidney clearance, and individualized treatment.
Featured Professional Education
Start with selected articles and research updates that highlight the breadth of evidence-based integrative nephrology.
Foundational Overview
Explore how conventional nephrology can be expanded through nutrition, lifestyle, genetics, environmental health, the gut–kidney axis, and individualized care.
Research & News
Review recent kidney research across nutrition, the microbiome, genetics and epigenetics, environmental exposures, lifestyle interventions, pharmaceuticals, and other clinically relevant developments.
Latest Articles
Explore recent articles on genetics and epigenetics, environmental exposures, nutrition, lifestyle interventions, pharmaceuticals, and their implications for kidney health and clinical care.
Integrative Nephrology
A Systems-Based Approach to Modern Kidney Care
Edited by Majd Isreb, MD, FACP, FASN, IFMCP
Published by Springer Nature
Integrative Nephrology brings together conventional kidney care with emerging evidence in nutrition, lifestyle medicine, genetics and epigenetics, environmental health, the gut microbiome, sleep, metabolic health, and other interconnected contributors to kidney disease.
Written for nephrologists, physicians, trainees, and integrative medicine practitioners, the book offers an evidence-based, systems-oriented framework for modern kidney care.
Stay Current in Integrative Nephrology
Kidney science is evolving quickly.
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Led by a Nephrologist. Built Around Evidence.
Majd Isreb, MD, FACP, FASN, IFMCP
Dr. Majd Isreb is a nephrologist with more than two decades of clinical experience and certification in functional medicine.
He founded the Integrative Kidney Institute to help patients and health professionals explore a more comprehensive approach to kidney health—one that remains grounded in nephrology while also examining nutrition, lifestyle, genetics and epigenetics, environmental exposures, the gut microbiome, and appropriate pharmaceutical care.
He is also the editor of Integrative Nephrology: A Systems-Based Approach to Modern Kidney Care, published by Springer Nature.
The goal of the Integrative Kidney Institute is not to replace conventional nephrology, but to expand the questions we ask, examine emerging evidence critically, and help translate that evidence into thoughtful kidney care.
Connect, Collaborate & Learn
The Integrative Kidney Institute welcomes professional inquiries, educational collaborations, speaking opportunities, interviews, and conversations about advancing evidence-based integrative approaches to kidney care.
Whether you are a clinician, educator, researcher, professional organization, or healthcare partner, we would be glad to hear from you.