About Integrative Kidney Institute
A broader, evidence-based approach to kidney health. The Integrative Kidney Institute connects conventional nephrology with emerging evidence across nutrition, lifestyle, genetics and epigenetics, environmental health, the gut–kidney axis, and individualized care.
Why Integrative Kidney Institute Exists
Kidney disease rarely exists in isolation.
The kidneys interact continuously with cardiovascular and metabolic health, nutrition, genetics, the gut, environmental exposures, medications, sleep, physical activity, and other aspects of human physiology.
Modern nephrology has transformed kidney care through increasingly effective diagnostics, medications, dialysis, transplantation, and disease-specific therapies. At the same time, a growing body of research is expanding our understanding of the broader biological and environmental factors that may influence kidney health.
The Integrative Kidney Institute was created to explore that broader landscape—without losing the scientific foundation of nephrology.
Look Beyond the Kidney
Explore the interconnected systems and exposures that may contribute to kidney health, disease risk, and progression.
Follow the Evidence
Distinguish established clinical practice from emerging research, plausible mechanisms, and questions that still require better evidence.
Translate Science Into Better Questions
Help patients and health professionals understand evolving kidney science and use it to support more informed conversations and decisions.
Who We Serve
Kidney health information should meet people where they are.
The Integrative Kidney Institute develops evidence-based education for people living with kidney disease, the professionals who care for them, and those working to advance our understanding of kidney health.
Patients & Families
Understand kidney health through accessible, evidence-based education that helps you ask better questions, evaluate health information critically, and participate more confidently in decisions about your care.
Health Professionals
Explore clinical education, research updates, and systems-oriented perspectives designed for nephrologists, physicians, dietitians, trainees, and other healthcare professionals.
Educators, Researchers & Organizations
Connect with the Institute for educational collaborations, speaking opportunities, interviews, professional initiatives, and conversations about advancing evidence-based kidney health.
Our Mission & Values
To advance a more comprehensive, evidence-based understanding of kidney health.
The Integrative Kidney Institute exists to make kidney science more accessible, explore emerging evidence critically, and connect insights from across medicine and human biology with the foundations of modern nephrology.
Evidence First
We distinguish established clinical evidence from emerging research, biological plausibility, and unanswered questions.
Think in Systems
Kidney health is connected to the rest of the body. We examine those relationships without losing sight of kidney physiology and established nephrology.
Inform, Not Oversimplify
We aim to give patients and health professionals the context they need to evaluate claims, ask better questions, and make informed decisions.
Stay Curious
Science evolves. We remain open to new ideas while applying the same critical standards to conventional, integrative, and emerging approaches.

Founder & Medical Director
Majd Isreb, MD, FACP, FASN, IFMCP
Nephrologist • Functional Medicine–Certified Physician • Educator
Dr. Majd Isreb founded the Integrative Kidney Institute to bring a broader, evidence-based perspective to kidney health.
With more than two decades of experience in nephrology and certification in functional medicine, his work connects established kidney care with evolving evidence across nutrition, lifestyle, genetics, environmental health, the gut–kidney axis, and pharmacologic therapy.
His approach is grounded in a simple principle: expanding the questions we ask about kidney disease should strengthen—not replace—the scientific foundations of nephrology.
Dr. Isreb is also editor of Integrative Nephrology—A Systems-Based Approach to Modern Kidney Care, published by Springer Nature.
Continue Exploring Integrative Kidney Health
Education, evidence, and resources for better-informed kidney health decisions.
Whether you are looking for kidney health education, professional resources, or opportunities to collaborate, explore the Institute’s growing library of evidence-based resources.
