We combed through multiple medical journals looking for the latest research on the Integrative approach to kidney health. We know your time is valuable, so we curated and summarized these studies for you. Welcome to the InKidney January Research and News.
Metabolic markers of ultra-processed food and incident CKD
In this research study published in CJASN this month, investigators looked at the link between metabolic markers of ultra-processed food intake and the incidence of chronic kidney disease (CKD).
The evaluated data from 3,751 participants in the Atherosclerosis Risk in Communities (ARIC) study. Dietary intake was assessed using a food frequency questionnaire, and ultra-processed food was classified using the NOVA classification system.
Then they identified the association between 359 metabolites and ultra-processed food consumption. After that they looked at the statistical association between these metabolites and incident CKD.
Higher levels of 3 metabolites mannose, glucose, N2, N2-dimethylguanosine were associated with high risk of incident CKD after a median follow up of 23 years.
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Nephrotoxicity of antimicrobials and antibiotics
This review article is a good resource for you to have. It summarizes the various mechanisms for nephrotoxicity of various antibiotics and antimicrobials.
The article also details preventative actions that be used to reduce long-term complications from these antibiotics. These include:
1. Dose adjustment according to kidney function.
2. Appropriate hydration during to course of therapy.
3. Avoiding the use of other nephrotoxins at the same time.
4. The use of as short of therapy as possible.
5. Some reports showed benefit of agents such as vitamin E, vitamin C, N-acetylcysteine, erythropoietin, α-lipoic acid, curcumin, or statins to prevent antimicrobial-induced acute kidney injury.
The full review article is available in the link below. Download it for free and keep it for your future use.
Zinc deficiency link to CKD and hypertensio
This review article published in Kidney 360 discussed the potential link between zinc deficiency, CKD and hypertension.
The article highlights the mechanisms of zinc procurement and trafficking. It provides evidence that urinary zinc wasting can fuel Zn deficiency in CKD. It also discusses how Zn deficiency can accelerate the progression of hypertension and kidney damage in CKD.
Finally, the authors discuss the consideration of zinc supplementation as an exit strategy with the potential to rectify the course of hypertension and CKD progression.
To read the full article please contact us. A link to the abstract is listed below.
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